Recent advancements in pharmacotherapy offer promising avenues for effective obesity management. In this presentation the latest medications approved for obesity treatment, their mechanisms of action, and clinical efficacy will be reviewed. Additionally, the presentation will address the integration of these pharmacological treatments with lifestyle interventions to achieve sustainable weight management and improved health outcomes. New applications for obesity management medications will be explored including obstructive sleep apnoea, heart failure and MAFLD. Whether obesity care can be personalized and practical tips and tricks for prescribing will be discussed.