Background and objectives: Increased arterial stiffness is an accepted cardiovascular risk factor. However, the effect of arterial stiffness on the performance of percutaneous coronary intervention (PCI) according to obesity is not well known. The aim of this study was to evaluate the impact of arterial stiffness measured by maximum pulse wave velocity (PWV) on acute gain after PCI.
Subjects and Methods: Data from 141 consecutive patients (240 lesions) who underwent PCI using drug eluting stents and PWV study were analyzed.
Results: Before Procedure, the minimal lumen diameter (MLD) was 0.87 ± 0.49 mm. After procedure, MLD was 2.34 ± 0.40 mm. Maximum PWV and acute gain were 1695 ± 389 cm s(-1) and 1.48± 0.55mm. There was negative correlation between maximum PWV and acute gain in the lesions of obese patients (correlation coefficient = -0.180; p=0.046). However, there was no correlation between maximum PWV and acute gain in the lesions of non-obese patients (correlation coefficient = -0.140; p=0.134)
Conclusions: Increased arterial stiffness is unfavorable for acute gain in the lesions of obese patients. However, this is not prognostic factor for that in the lesions of non-obese patients. Therefore, we should make more effort to get sufficient acute gain when faced with the obese patients during PCI.