Lightning Talk + Poster ESA-SRB-ANZBMS 2024 in conjunction with ENSA

Relationship between 24-h movement behaviours and glycaemic control in older adults with type 2 diabetes (#494)

Morton G Burt 1 2 , Jasmine Petersen 3 , Sophie M Drake 1 , Dorothea Dumuid 4 , Lucy K Lewis 3
  1. Southern Adelaide Diabetes and Endocrine Services, Flinders Medical Centre, Adelaide, SA, Australia
  2. College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia
  3. Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia
  4. Alliance for Research in Exercise, Nutrition and Activity, University of South Australia, Adelaide, SA, Australia

Reducing sedentary behaviour is potentially an achievable intervention to improve glycaemic control in older adults with type 2 diabetes. However, lower glucose levels have mainly been reported with large reductions in sedentary behaviour (1). We determined the relationship between 24-h movement behaviour and glycaemic variables and quantified how theoretical reallocations of time between behaviours were associated with differences in these measures.

This is a secondary analysis of 24 adults with type 2 diabetes (age 70±5 years, 15 females) in a prospective study. Interstitial glucose was measured using an iPro2 continuous glucose monitoring system (Medtronic/Minimed, USA) and physical activity with a thigh-worn activPAL3 inclinometer (PAL Technologies, Scotland) for two 6-day periods before and after a 6-week incremental goal-setting intervention designed to reduce sedentary behaviour. Compositional isometric log ratios were generated for mean 24-hour sleeping, sitting, standing and stepping time and regressed against mean glucose, time in glucose range (TIGR, glucose 4-10 mmol/L) and mean daily standard deviation for glucose (glucose SD) to determine the association between glycaemic variables and a 30-minute change in behaviours.

Participants spent 8.4±1.4 h/day sleeping, 10.5±2.0 h/day sitting, 3.7±1.7 h/day standing and 1.4±0.5 h/day stepping. Mean glucose was positively associated with sitting with a 30-minute reduction in sitting time associated with a 0.12 mmol/L (95% confidence intervals 0.02-0.21) reduction in mean glucose. A 30-minute reduction in sitting was associated with a 1.5% (0.3-2.6) increase and a 30-minute increase in stepping associated with a 5.7% (1.0-10.4) increase in TIGR. A 30-minute increase in stepping was associated with a 0.31 mmol/L (0.11-0.52) reduction in glucose SD.

Less sitting time is associated with a small reduction in mean glucose and increase in TIGR. More stepping time is associated with a larger increase in TIGR and reduced glycaemic variability and is likely to have a greater beneficial effect on glycaemic control.

  1. Duvivier BM, Schaper NC, Hesselink MK , et al. Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes. Diabetologia 2017;60:490-498.